Hey there! Welcome!
Get updated on
Select Speciality
Top Picks
3 Feb, 26
This IDSA guideline outlines evidence‑based empiric and definitive antibiotic selection for complicated UTI, emphasizing severity‑based therapy, resistance risk assessment, patient‑specific factors, and stewardship‑driven narrowing once cultures return.
3 Feb, 26
18 Feb, 26
Diabetes Metab Syndr...
- The umbrella review of 20 systematic reviews (675 studies) found high prevalence of cardiometabolic & renal long-term conditions in T2DM patients
- Cardiovascular disease pooled prevalence ranged from 13.0% to 46.0% & HF up to 25.0, nephropathy pooled prevalence ranged from 4.2% to 38.0% & CKD 18.2% to 35.5%
- Rates were higher in males & LMICs, targeted management may address the comorbidities effectively.
18 Feb, 26Oral Dis.
- Systematic review (n=983 cases; 968 oral surgery) assessed bleeding risk in dental interventions with platelet counts <50,000/μL
- Post-op bleeding occurred in 65 cases (12.9% vs 4.9% for ≥50,000/μL; RR 2.95; p<0.0001), including 1 life-threatening event
- Low platelets increase bleeding risk but are not absolute contraindication; individualized assessment is essential.
17 Feb, 26Diabetes Metab Syndr...
- Systematic review/meta-analysis of 15 studies (12 outcomes) on alpha-lipoic acid (ALA) in diabetic polyneuropathy was conducted
- ALA 600 mg/day improved TSS paresthesia (SMD = −1.04; p<0.00001), numbness (SMD = −0.23; p=0.04) & HPAL (SMD = −1.00; p<0.00001)
- No effect on HbA1c, NO, sural SNAP, peroneal MNCV
- ALA is a safe adjunct for symptom relief but its impact on nerve conduction/glycemic control is inconclusive.
13 Feb, 26N Engl J Med
- Streptococcus agalactiae bacteraemia was common in elderly men, especially in the skin and soft tissue & reported a high 30 day mortality rate (9%)
- Time to blood culture positivity (TTP) was shorter in infective endocarditis (IE, 7.5 h vs 9.1 h, p=0.005) but did not differ between survivors & nonsurvivors
- The study suggested a potential role of TTP in identifying patients at IE risk in S. agalactiae bacteraemia.
5 Feb, 26
Featured
17 Feb, 26
13 Feb, 26
11 Feb, 26
