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23 Feb, 26
The updated international urticaria guideline describes its definition, classification and recommendations for diagnosing and managing its various subtypes.
3 Feb, 26
20 Feb, 26
Br. J. Dermatol.
- In atopic dermatitis, global comorbidity prevalence was 20.1% asthma, 45.1% rhinitis, 41.4% allergic rhinitis, 30.7% rhinoconjunctivitis, and 10.4% combined asthma–rhinitis.
- Highest rates occurred in India, Cuba, Finland, Puerto Rico.
- AD increased odds of asthma (OR 2.73), rhinitis (OR 2.98), allergic rhinitis (OR 2.42), rhinoconjunctivitis (OR 4.21), and combined disease (OR 2.42).
18 Feb, 26Oral Dis.
- Systematic review (n=983 cases; 968 oral surgery) assessed bleeding risk in dental interventions with platelet counts <50,000/μL
- Post-op bleeding occurred in 65 cases (12.9% vs 4.9% for ≥50,000/μL; RR 2.95; p<0.0001), including 1 life-threatening event
- Low platelets increase bleeding risk but are not absolute contraindication; individualized assessment is essential.
18 Feb, 26Diabetes Metab Syndr...
- The umbrella review of 20 systematic reviews (675 studies) found high prevalence of cardiometabolic & renal long-term conditions in T2DM patients
- Cardiovascular disease pooled prevalence ranged from 13.0% to 46.0% & HF up to 25.0, nephropathy pooled prevalence ranged from 4.2% to 38.0% & CKD 18.2% to 35.5%
- Rates were higher in males & LMICs, targeted management may address the comorbidities effectively.
17 Feb, 26Diabetes Metab Syndr...
- Systematic review/meta-analysis of 15 studies (12 outcomes) on alpha-lipoic acid (ALA) in diabetic polyneuropathy was conducted
- ALA 600 mg/day improved TSS paresthesia (SMD = −1.04; p<0.00001), numbness (SMD = −0.23; p=0.04) & HPAL (SMD = −1.00; p<0.00001)
- No effect on HbA1c, NO, sural SNAP, peroneal MNCV
- ALA is a safe adjunct for symptom relief but its impact on nerve conduction/glycemic control is inconclusive.
5 Feb, 26
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