DETeCD-ADRD guideline provides a structured, multi-tiered approach for diagnosing and evaluating suspected Alzheimer’s Disease and Related Dementias (ADRD) in primary care, emphasizing patient-centered communication, validated cognitive assessments, and individualized laboratory and imaging tests. It also outlines a stepwise diagnostic disclosure process, ensuring patients and caregivers receive clear information abo...

Over half (54.7%) of head and neck squamous cell carcinoma (HNSCC) patients treated with radiotherapy (RT) developed thyroid dysfunction (TD), with 53.7% experiencing long-term effects. Subclinical hypothyroidism was most common, progressing to overt hypothyroidism in 21%. T2DM, metastatic lymph nodes, & lack of tumor resection increased TD risk, emphasizing the need for routine thyroid monitoring post-RT.

A cervical screening trial confirmed the feasibility of vaginal self-testing for high-risk human papillomavirus (HPV), with 95% opting for self-collection. HPV was detected in 12.9%, and 95% of those affected underwent follow-up, 2.6% of participants with HPV 16/18 attended colposcopy, while 92% with other HPV types completed cytology, supporting integration of self-test in cervical screening programmes.

A multilevel analysis of National Family Health Survey India (2019–21) showed adverse neonatal outcomes—preterm birth, low birth weight & early neonatal deaths—rising from 20% in 2005-2006 to 26.5%. Higher maternal education & antenatal care reduced risks, while poverty & unintended pregnancy increased them. Accounting for district, community & household factors reduced variability in outcomes by 4.7%, 18.8% & 30.9%....

Low-density lipoprotein cholesterol (LDL-C) below 70 mg/dL was linked to a 26% lower risk of dementia and a 28% lower risk of Alzheimer’s disease-related dementia (ADRD) compared to levels above 130 mg/dL. Levels below 55 mg/dL further reduced risk by 18%. Among those with LDL-C <70 mg/dL, statin use reduced dementia risk by 13% and ADRD risk by 12%, highlighting lipid management’s role in dementia prevention.