Key session presented at the European Academy of Dermatology and Venereology (EADV) Congress 2024, 25-28th September 2024, Amsterdam, Netherlands

Key session presented at the European Academy of Dermatology and Venereology (EADV) Congress 2024, 25-28th September 2024, Amsterdam, Netherlands

New research found that patients with late-stage systemic sclerosis (SSc) may develop ILD, thus challenging previous assumptions about its emergence. Tracking 969 patients over 16 yrs, 21% developed ILD within an average of 2.4 years, with a lower incidence rate in late SSc compared to earlier stages. Despite this, the severity & progression rates of lung disease were similar between late-onset & early-onset cases.

A large study analyzing health records from over 17,900 adults - none with a prior history of cardiovascular disease (CVD)- found that the incidence of CVD was significantly higher in individuals diagnosed with tuberculosis (TB), particularly during the acute period, defined as the 3 months before & after TB diagnosis. Even after adjusting for pre-existing CVD risk factors, the rates remained significantly elevated.

Despite a 39.8% reduction in global stillbirths since 1990, a new report from the Global Burden of Disease Study 2021 highlighted that stillbirth rates remain disturbingly high, with 3.04 million stillbirths occurring at or beyond 20 weeks' gestation in 2021. The majority - 77.4% - occurred in South Asia & sub-Saharan Africa. Nearly one million stillbirths, or 30.5% of the total, occurred between 20 & 28 weeks.

In women with HIV, switching to integrase strand transfer inhibitors (INSTIs) during the menopausal transition is associated with accelerated changes in body composition. While waist circumference (WC) changes were similar during premenopause, those on INSTIs had faster increases in WC & BMI during late perimenopause & menopause, peaking at 43 months. Considering menopausal status when prescribing INSTIs is crucial.